Introducing ActiGin®, NuLiv Science’s proprietary sports activities nutraceutical comprised of two extremely purified and fractionated extracts from Panax notoginseng and Rosa roxburghii by NuLiv’s pharmaceutical extraction and processing expertise.
What can ActiGin do to assist your efficiency
ActiGin® is the results of greater than 10 years of analysis that has proven in a single in-vivo and 5 human scientific trials to:
- Improve endurance time (time to exhaustion) in a single high-intensity biking train (80% VO2 max) by 20%*
- Improve power (ATP) manufacturing by elevating the pace-making enzyme Citrate synthase in step one of the citric acid cycle by 42%*
- Pace up restoration by lowering irritation in muscle as evidenced by the discount of the inflammatory biomarkers TBARS (24%), MDA (44%), Interleukin 6 (IL-6) (35%), and Creatine kinase (CK) (69%)*
- Eradicate senescent muscle cells via macrophage phagocytosis in a fourth human scientific trial revealed within the Journal of Ginseng Analysis. Particularly, to lower SA-β-gal and collagenase, reverse apoptotic DNA fragmentation and leukocyte infiltration, and enhance iNOS and IL-6 mRNA expression within the quadriceps after 60-minute biking at 70% VO2 max*
- Successfully facilitate senescent cell clearance in contracting muscle tissue and helps keep muscle stem cell numbers throughout train to boost high-intensity endurance efficiency.*
Blood glucose is saved as glycogen in muscle. It’s the gas for the muscle to perform throughout intense (anaerobic) train. Train induces irritation on muscle membrane the place insulin receptor and glucose transporter (GLUT4) are positioned and disrupts the availability of blood glucose into the muscle.
Pre-clinical and scientific trials counsel that ActiGin® preserves the insulin receptor and glucose transporter on muscle membrane throughout intensive train to make sure a steady provide of blood glucose into the muscle for it to perform correctly.
That is supported by the decreased irritation and elevated glycogen buildup in muscle and in addition by the clearance of senescent muscle cell via macrophage phagocytosis within the newest human scientific trial revealed within the Journal of Ginseng Analysis.
How ActiGin® Works
One in-vivo and three human scientific trials on ActiGin® counsel that its results on enhancing endurance/stamina, power and restoration time in high-intensity workout routines could also be resulting from its means to protect insulin receptors and glucose transporters on muscle membrane throughout intensive workout routines to make sure a steady provide of blood glucose into the muscle.
Glucose is the gas for muscle throughout intensive train. Depletion of glucose has detrimental results on muscle tissue to contract and work correctly. There are senescent cells in all human tissues at sure proportions, notably for these short-lived endothelial cells (lifespan < 2 weeks) in blood vessels of tissues. ActiGin® considerably decreased senescent cell inhabitants (largely endothelial progenitor cells) of exercising skeletal muscle (Journal of Ginseng Analysis).
Excessive-intensity train acutely decreases satellite tv for pc cell numbers resulting from elevated demand on nucleus for muscle regeneration throughout challenges. ActiGin® utterly attenuated acute satellite tv for pc cell depletion (Journal of Purposeful Meals).
These findings counsel that ActiGin® successfully facilitates senescent cell clearance in contracting muscle tissue and helps keep muscle stem cell numbers throughout train to boost high-intensity endurance efficiency.*
